Thorne Riboflavin 5-Phosphate R5P - Bioactive B2 for MTHFR & Energy | 60 Capsules

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Active R5P form bypasses liver conversion for instant absorption.
Critical cofactor for the MTHFR enzyme and folate metabolism.
Supports mitochondrial energy (ATP) production and eye health.
Essential for activating Vitamin B6 and other B-complex vitamins.
Often used in nutritional protocols for head comfort and frequency.
Pure, hypoallergenic formula free from gluten, soy, and binders.

Delivery in 2–4 days Easy returns Ask a pharmacist

Description

Unlock superior cellular energy with Thorne Riboflavin 5-Phosphate R5P, the bioactive form of Vitamin B2 designed for optimal absorption and enzymatic function. Unlike standard Riboflavin, which the body must convert, this tissue-ready formula delivers immediate support for your metabolism and nervous system.

Best Vitamin B2 for MTHFR & Methylation Support

Many individuals have a genetic difficulty converting standard vitamins into their active forms. R5P is the Active B2 cofactor required for the proper function of the MTHFR enzyme.

Folate Activation: Without adequate active Riboflavin, the body struggles to process Folate (B9), impacting the entire methylation cycle.
Vitamin Synergy: This formula is essential for converting Vitamin B6 into its active form (P5P), creating a comprehensive B-vitamin support system.

Mitochondrial Energy & Head Comfort

Research suggests that Riboflavin for migraines protocols may support mitochondrial efficiency in the brain. By enhancing the production of cellular energy (ATP), Riboflavin 5'-Phosphate helps maintain healthy neurological function. This Mitochondrial energy supplement is widely utilized by practitioners to support healthy mucous membranes and eye structure while combating cellular fatigue.

Pure Ingredients, Clinical Standards

Thorne Research is renowned for its "No List" of banned ingredients. This formula is gluten-free, soy-free, and contains no stearates.

Riboflavin 5'-Phosphate Sodium (36.5 mg): The body-ready active form.
Calcium Laurate: A natural, safe manufacturing aid.
Hypromellose Capsule: Vegetarian and clean.

How to Use

Take 1 capsule one to three times daily, or as recommended by your health practitioner. For specific protocols, practitioners often titrate this specific active form differently than generic Riboflavin.

Note: Harmlessly turns urine a bright neon yellow (Flavinuria)—this is a sign the vitamin is being absorbed and excreted safely. Consult a doctor if pregnant.

Read the clinical data regarding B2 efficacy here: NIH Study: Riboflavin (Vitamin B2) for the prevention of migraine.

Attributes

Form: Capsules
Ingredients: Riboflavin 5'-Phosphate Sodium

Please note

Important: manufacturers may change a product's shape, its formula, or its label at any time and without prior notice. The details on this page are for guidance only, and the item you receive may differ from what is shown here. Our guarantee is that you receive the same product you intended to order, and that it is authentic — sourced directly from the manufacturer or one of its authorized resellers or official distributors. Always read the label on the product you receive before use.

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